Har Gobind Khorana

Who is Har Gobind Khorana ?

  • Name: Dr. Hargovind Khurana.
  • Born: February 9, 1922.
  • Birth: Raipur (G.Multan, Punjab).
  • Father: Lala Ganpatrai.
  • Education: In 1945 M. Sc. And in 1948 PHD.
  • Wife: with Esther (in 1952).

Early Life

Har Gobind Khorana was born on 9 January 1922 at a place called Raipur (District Multan, Punjab) in undivided India. His father was a Patwari. Hargovind was the youngest of four sons of his parents. Despite poverty, Hargovind's father paid attention to the education of his children.

Due to which Khurana focused all his attention on studies. His father died when he was just 12 years old, and in such a situation his elder brother Nandlal took charge of his education. He got his early education in a local school. He was the D.A.V. of Multan. Also studied in high school. He was a talented student since childhood, due to which he got equal scholarships.

He received his BS-C from Punjab University in 1943. (Hons) and in 1945 MS-C. (Honors) degree. Mahan Singh was his inspector in the Punjab University. After this he went to England for higher education after getting a scholarship from the Government of India. In England, he was Professor Roger JS at the University of Liverpool. Did research in beer care and earned a doctorate degree. Subsequently, he again received a PhD from the Government of India, after which he ventured into exploration with Professor V. Prelog at the Federal Institute of Technology in Zurich (Switzerland).

In 1960, he was awarded the Gold Medal in the 'Professor Institute of Public Service' Canada and was also awarded the 'Merck Award'. After this, in 1960, Dr. Khurana was appointed as Professor in the Institute of Enzyme Research at the University of Wisconsin, USA. In 1966, he took American citizenship.

In England, he was Professor Roger JS at the University of Liverpool. Did research in beer care and earned a doctorate degree. Subsequently, he again received research from the Government of India, after which he was involved in exploration with Professor V. Prelog at the Federal Institute of Technology in Zurich (Switzerland).

Work :

Doctor Khurana ji was engaged in the study of the chemical composition of the nuclei of organisms. The discovery of nuclei with respect to nuclear acids has been taking place for a long time, but this was made possible by the special methods of Dr. Khurana. The subject of their study is the extremely complex, basic, chemical structures of subsets called nucleotids. By combining these aggregates, Dr. Khurana succeeded in making compounds called nucleiprotid enzymes of two classes of importance.

Nuclear acid methyls are made up of single nucleotids. The genetic properties of biofilms depend on the structure of these complex multi nucleotides. Dr. Khurana succeeded in adding eleven nucleotides and now he was able to synthesize in the laboratory the nucleic acid containing known chain nucleotides. With this success, it has been possible to understand the relationship between the structure and genetic properties of amino acids, and scientists will now be able to find the cause of genetic diseases and ways to overcome them.

In 1960, he was awarded the Gold Medal at the 'Professor Institute of Public Service' Canada. Doctor Khurana received full support from his wife. His wife was also a scientist. And understood her husband's feelings. His fame had reached America. In 1958, he received a letter from the US institution 'Rockefeller'. This institute had invited him as a visiting professor. Khurana went there and gave his speeches related to science. His talk had a profound effect on the director of the institution.

Genes are made up of many types of acids. During the search, it was found that Jins D.N.A. And R.N.A. Are made by chance. Hence, they are considered to be the basic unit of life. The basic secret of heredity is hidden in these acids. The research of artificial commodities done by Khurana revealed that the anatomy, complexion and qualities of human beings are related to nature. His fame had reached America. In 1958, he received a letter from the US institution 'Rockefeller'. This institute had invited him as a visiting professor. Khurana went there and gave his speeches related to science. His talk had a profound effect on the director of the institution.

On commodities, it depends on how a person's nature is and how he looks. Parents get children only by coincidence with their commodities. Therefore, it is natural for children to have the qualities of parents. If a person does not want his defects in his child, then it is possible to produce special qualities in him in today's scientific age.

Har Gobind Khorana Contribution:

In the 1960s, Khurana confirmed Neerberg's discovery that the D.N.A. The manner of configuration of four different types of nucleotides at the curved 'step' of the molecule determines the chemical structure and function of the new cell. Dna 64 possible combinations of nucleotides have been studied to produce the desired amino acid on a fiber of K, which are the building blocks of the protein.

Khurana gave further information about which sequential combination of nucleotides makes which particular amino acid. They also confirmed that nucleotides are always transmitted to the code cell in a group of three, which is called a codon. They also discovered that some molecules cause the cell to start or stop producing proteins.

Genes are made up of many types of acids. During the search, it was found that Jins D.N.A. And R.N.A. Are made by chance. Hence, they are considered to be the basic unit of life. The basic secret of heredity is hidden in these acids. Research of artificial commodities made by Khurana revealed that the anatomy, complexion and qualities of humans are related to nature.

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Khurana made another contribution to genetics in 1970, when he and his research team were successful in synthesizing the first artificial copy of a yeast gene. Dr. Khurana was last served as Alfred P. Sloan Professor of Biology and Chemistry and at Liverpool University.

Dr. Har Gobind Khorana, an American citizen of Indian origin, who explains the genetic code (DNA), was given the Nobel Prize in Physiology or Medicine for research in medicine. Khurana worked in the field of medicine with Marshall, Nirenberg and Robert Holley. He also received the Horwitz Award from the University of Colombia in 1968.

He is survived by daughter Julia and son Dave. Khurana was born in Raipur in Punjab province of unified India in 1922. That area is now in Pakistan. Khurana is known as a scientist who revolutionized the field of biochemistry with his excellent work in DNA chemistry. Aseem Ansari, a professor of biochemistry at the University of Wisconsin-Madison, said that the work he did at Viscocin from 1960 to 1970 continues to inspire new scientific discoveries and progress.

He started research on nucleic acids during his education at Cambridge University (1951) under Sir Alexander Todd. He held Fellow and Professor positions at the Swiss Federal Institute of Technology in Switzerland and in British Columbia, Canada (1952–1959) and in Winskonsill, USA. In 1971, he joined the faculty of the Massachusetts Institute of Technology. Khurana did teaching work in Viscongsin and did research there from 1960 to 1970. He then moved to the Massachusetts Institute of Technology (MIT).

In Viscocin itself, Khurana, along with his colleagues, worked on the mechanism of RNA code for protein synthesis. For this, he was awarded the Nobel Prize. He was given the honor along with Robert Hawley of Cornell University and Marshall Nirenberg of the National Institutes of Health. Hargobind Khurana died on November 9, 2011.

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